Inflammatory findings on species extrapolations: humans are definitely no 70-kg mice

by Leist, Marcel, Hartung, Thomas
Published 2013

From smoking guns to footprints: mining for critical events of toxicity pathways in transcriptome data

by Rahnenführer, Jörg, Leist, Marcel
Published 2015

Metabolic Depletion of Atp by Fructose Inversely Controls Cd95- and Tumor Necrosis Factor Receptor 1–Mediated Hepatic Apoptosis

by Latta, Markus, Künstle, Gerald, Leist, Marcel, Wendel, Albrecht
Published 2000

Botulinum neurotoxin C initiates two different programs for neurite degeneration and neuronal apoptosis

by Berliocchi, Laura, Fava, Eugenio, Leist, Marcel, Horvat, Volker, Dinsdale, David, Read, David, Nicotera, Pierluigi
Published 2005

Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis

by Leist, Marcel, Single, Barbara, Castoldi, Anna F., Kühnle, Simone, Nicotera, Pierluigi
Published 1997

Asialoerythropoetin is not effective in the R6/2 line of Huntington's disease mice

by Gil, Joana MAC, Leist, Marcel, Popovic, Natalija, Brundin, Patrik, Petersén, Åsa
Published 2004

Evaluation of Developmental Toxicants and Signaling Pathways in a Functional Test Based on the Migration of Human Neural Crest Cells

by Zimmer, Bastian, Lee, Gabsang, Balmer, Nina V, Meganathan, Kesavan, Sachinidis, Agapios, Studer, Lorenz, Leist, Marcel
Published 2012

Astrocyte Differentiation of Human Pluripotent Stem Cells: New Tools for Neurological Disorder Research

by Chandrasekaran, Abinaya, Avci, Hasan X., Leist, Marcel, Kobolák, Julianna, Dinnyés, Andras
Published 2016

Highlight report: Launch of a large integrated European in vitro toxicology project: EU-ToxRisk

by Daneshian, Mardas, Kamp, Hennicke, Hengstler, Jan, Leist, Marcel, van de Water, Bob
Published 2016

Cathepsin B Acts as a Dominant Execution Protease in Tumor Cell Apoptosis Induced by Tumor Necrosis Factor

by Foghsgaard, Lasse, Wissing, Dorte, Mauch, Daniel, Lademann, Ulrik, Bastholm, Lone, Boes, Marianne, Elling, Folmer, Leist, Marcel, Jäättelä, Marja
Published 2001

Identification of transcriptome signatures and biomarkers specific for potential developmental toxicants inhibiting human neural crest cell migration

by Pallocca, Giorgia, Grinberg, Marianna, Henry, Margit, Frickey, Tancred, Hengstler, Jan G., Waldmann, Tanja, Sachinidis, Agapios, Rahnenführer, Jörg, Leist, Marcel
Published 2015

Lineage-Specific Regulation of Epigenetic Modifier Genes in Human Liver and Brain

by Weng, Matthias K., Natarajan, Karthick, Scholz, Diana, Ivanova, Violeta N., Sachinidis, Agapios, Hengstler, Jan G., Waldmann, Tanja, Leist, Marcel
Published 2014

Extensive Transcriptional Regulation of Chromatin Modifiers during Human Neurodevelopment

by Weng, Matthias K., Zimmer, Bastian, Pöltl, Dominik, Broeg, Marc P., Ivanova, Violeta, Gaspar, John A., Sachinidis, Agapios, Wüllner, Ullrich, Waldmann, Tanja, Leist, Marcel
Published 2012

A 3-dimensional human embryonic stem cell (hESC)-derived model to detect developmental neurotoxicity of nanoparticles

by Hoelting, Lisa, Scheinhardt, Benjamin, Bondarenko, Olesja, Schildknecht, Stefan, Kapitza, Marion, Tanavde, Vivek, Tan, Betty, Lee, Qian Yi, Mecking, Stefan, Leist, Marcel, Kadereit, Suzanne
Published 2012

Design Principles of Concentration-Dependent Transcriptome Deviations in Drug-Exposed Differentiating Stem Cells

by Waldmann, Tanja, Rempel, Eugen, Balmer, Nina V., König, André, Kolde, Raivo, Gaspar, John Antonydas, Henry, Margit, Hescheler, Jürgen, Sachinidis, Agapios, Rahnenführer, Jörg, Hengstler, Jan G., Leist, Marcel
Published 2014

Instruments for Assessing Risk of Bias and Other Methodological Criteria of Animal Studies: Omission of Well-Established Methods

by Beck, Nancy B., Becker, Richard A., Boobis, Alan, Fergusson, Dean, Fowle, John R., Goodman, Julie, Hoffmann, Sebastian, Lalu, Manoj, Leist, Marcel, Stephens, Martin L.
Published 2014

From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effe...

by Balmer, Nina V., Klima, Stefanie, Rempel, Eugen, Ivanova, Violeta N., Kolde, Raivo, Weng, Matthias K., Meganathan, Kesavan, Henry, Margit, Sachinidis, Agapios, Berthold, Michael R., Hengstler, Jan G., Rahnenführer, Jörg, Waldmann, Tanja, Leist, Marcel
Published 2014

Preferential Extracellular Generation of the Active Parkinsonian Toxin MPP+ by Transporter-Independent Export of the Intermediate MPDP+

by Schildknecht, Stefan, Pape, Regina, Meiser, Johannes, Karreman, Christiaan, Strittmatter, Tobias, Odermatt, Meike, Cirri, Erica, Friemel, Anke, Ringwald, Markus, Pasquarelli, Noemi, Ferger, Boris, Brunner, Thomas, Marx, Andreas, Möller, Heiko M., Hiller, Karsten, Leist, Marcel
Published 2015

Major Histocompatibility Complex class I proteins are critical for maintaining neuronal structural complexity in the aging brain

by Lazarczyk, Maciej J., Kemmler, Julia E., Eyford, Brett A., Short, Jennifer A., Varghese, Merina, Sowa, Allison, Dickstein, Daniel R., Yuk, Frank J., Puri, Rishi, Biron, Kaan E., Leist, Marcel, Jefferies, Wilfred A., Dickstein, Dara L.
Published 2016

A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors

by Rempel, Eugen, Hoelting, Lisa, Waldmann, Tanja, Balmer, Nina V., Schildknecht, Stefan, Grinberg, Marianna, Das Gaspar, John Antony, Shinde, Vaibhav, Stöber, Regina, Marchan, Rosemarie, van Thriel, Christoph, Liebing, Julia, Meisig, Johannes, Blüthgen, Nils, Sachinidis, Agapios, Rahnenführer, Jörg, Hengstler, Jan G., Leist, Marcel
Published 2015