Evaluation of Developmental Toxicants and Signaling Pathways in a Functional Test Based on the Migration of Human Neural Crest Cells

by Zimmer, Bastian, Lee, Gabsang, Balmer, Nina V, Meganathan, Kesavan, Sachinidis, Agapios, Studer, Lorenz, Leist, Marcel
Published 2012

Design Principles of Concentration-Dependent Transcriptome Deviations in Drug-Exposed Differentiating Stem Cells

by Waldmann, Tanja, Rempel, Eugen, Balmer, Nina V., König, André, Kolde, Raivo, Gaspar, John Antonydas, Henry, Margit, Hescheler, Jürgen, Sachinidis, Agapios, Rahnenführer, Jörg, Hengstler, Jan G., Leist, Marcel
Published 2014

From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effe...

by Balmer, Nina V., Klima, Stefanie, Rempel, Eugen, Ivanova, Violeta N., Kolde, Raivo, Weng, Matthias K., Meganathan, Kesavan, Henry, Margit, Sachinidis, Agapios, Berthold, Michael R., Hengstler, Jan G., Rahnenführer, Jörg, Waldmann, Tanja, Leist, Marcel
Published 2014

A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors

by Rempel, Eugen, Hoelting, Lisa, Waldmann, Tanja, Balmer, Nina V., Schildknecht, Stefan, Grinberg, Marianna, Das Gaspar, John Antony, Shinde, Vaibhav, Stöber, Regina, Marchan, Rosemarie, van Thriel, Christoph, Liebing, Julia, Meisig, Johannes, Blüthgen, Nils, Sachinidis, Agapios, Rahnenführer, Jörg, Hengstler, Jan G., Leist, Marcel
Published 2015

Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach

by Krug, Anne K., Kolde, Raivo, Gaspar, John A., Rempel, Eugen, Balmer, Nina V., Meganathan, Kesavan, Vojnits, Kinga, Baquié, Mathurin, Waldmann, Tanja, Ensenat-Waser, Roberto, Jagtap, Smita, Evans, Richard M., Julien, Stephanie, Peterson, Hedi, Zagoura, Dimitra, Kadereit, Suzanne, Gerhard, Daniel, Sotiriadou, Isaia, Heke, Michael, Natarajan, Karthick, Henry, Margit, Winkler, Johannes, Marchan, Rosemarie, Stoppini, Luc, Bosgra, Sieto, Westerhout, Joost, Verwei, Miriam, Vilo, Jaak, Kortenkamp, Andreas, Hescheler, Jürgen, Hothorn, Ludwig, Bremer, Susanne, van Thriel, Christoph, Krause, Karl-Heinz, Hengstler, Jan G., Rahnenführer, Jörg, Leist, Marcel, Sachinidis, Agapios
Published 2012