Proteasomal inhibition potentiates drugs targeting DNA topoisomerase II

by Lee, Ka C., Bramley, Rebecca L., Cowell, Ian G., Jackson, Graham H., Austin, Caroline A.
Published 2016

The fate of human Langerhans cells in hematopoietic stem cell transplantation

by Collin, Matthew P., Hart, Derek N.J., Jackson, Graham H., Cook, Gordon, Cavet, James, Mackinnon, Stephen, Middleton, Peter G., Dickinson, Anne M.
Published 2006

Implementation of genome-wide complex trait analysis to quantify the heritability in multiple myeloma

by Mitchell, Jonathan S., Johnson, David C., Litchfield, Kevin, Broderick, Peter, Weinhold, Niels, Davies, Faith E., Gregory, Walter A., Jackson, Graham H., Kaiser, Martin, Morgan, Gareth J., Houlston, Richard S.
Published 2015

Genome-wide ChIP-seq analysis of human TOP2B occupancy in MCF7 breast cancer epithelial cells

by Manville, Catriona M., Smith, Kayleigh, Sondka, Zbyslaw, Rance, Holly, Cockell, Simon, Cowell, Ian G., Lee, Ka Cheong, Morris, Nicholas J., Padget, Kay, Jackson, Graham H., Austin, Caroline A.
Published 2015

MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA

by Lee, Ka Cheong, Padget, Kay, Curtis, Hannah, Cowell, Ian G., Moiani, Davide, Sondka, Zbyslaw, Morris, Nicholas J., Jackson, Graham H., Cockell, Simon J., Tainer, John A., Austin, Caroline A.
Published 2012

Effects of zoledronic acid versus clodronic acid on skeletal morbidity in patients with newly diagnosed multiple myeloma (MRC Myeloma IX): secondary outcomes from a randomised cont...

by Morgan, Gareth J, Child, J Anthony, Gregory, Walter M, Szubert, Alex J, Cocks, Kim, Bell, Sue E, Navarro-Coy, Nuria, Drayson, Mark T, Owen, Roger G, Feyler, Sylvia, Ashcroft, A John, Ross, Fiona M, Byrne, Jennifer, Roddie, Huw, Rudin, Claudius, Cook, Gordon, Jackson, Graham H, Wu, Ping, Davies, Faith E
Published 2011

First-line treatment with zoledronic acid as compared with clodronic acid in multiple myeloma (MRC Myeloma IX): a randomised controlled trial

by Morgan, Gareth J, Davies, Faith E, Gregory, Walter M, Cocks, Kim, Bell, Sue E, Szubert, Alex J, Navarro-Coy, Nuria, Drayson, Mark T, Owen, Roger G, Feyler, Sylvia, Ashcroft, A John, Ross, Fiona, Byrne, Jennifer, Roddie, Huw, Rudin, Claudius, Cook, Gordon, Jackson, Graham H, Child, J Anthony
Published 2010

A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial

by Boyd, Kevin D, Ross, Fiona M, Chiecchio, Laura, Dagrada, GianPaolo, Konn, Zoe J, Tapper, William J, Walker, Brian A, Wardell, Christopher P, Gregory, Walter M, Szubert, Alex J, Bell, Sue E, Child, J Anthony, Jackson, Graham H, Davies, Faith E, Morgan, Gareth J
Published 2011

Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk

by Broderick, Peter, Chubb, Daniel, Johnson, David C, Weinhold, Niels, Försti, Asta, Lloyd, Amy, Olver, Bianca, Ma, Yussanne, Dobbins, Sara E, Walker, Brian A, Davies, Faith E, Gregory, Walter A, Childs, J. Anthony, Ross, Fiona M, Jackson, Graham H, Neben, Kai, Jauch, Anna, Hoffmann, Per, Mühleisen, Thomas W, Nöthen, Markus M, Moebus, Susanne, Tomlinson, Ian P, Goldschmidt, Hartmut, Hemminki, Kari, Morgan, Gareth J, Houlston, Richard S
Published 2011

APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma

by Walker, Brian A, Wardell, Christopher P, Murison, Alex, Boyle, Eileen M, Begum, Dil B, Dahir, Nasrin M, Proszek, Paula Z, Melchor, Lorenzo, Pawlyn, Charlotte, Kaiser, Martin F, Johnson, David C, Qiang, Ya-Wei, Jones, John R, Cairns, David A, Gregory, Walter M, Owen, Roger G, Cook, Gordon, Drayson, Mark T, Jackson, Graham H, Davies, Faith E, Morgan, Gareth J
Published 2015

Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma

by Johnson, David C., Weinhold, Niels, Mitchell, Jonathan S., Chen, Bowang, Kaiser, Martin, Begum, Dil B., Hillengass, Jens, Bertsch, Uta, Gregory, Walter A., Cairns, David, Jackson, Graham H., Försti, Asta, Nickel, Jolanta, Hoffmann, Per, Nöethen, Markus M., Stephens, Owen W., Barlogie, Bart, Davis, Faith E., Hemminki, Kari, Goldschmidt, Hartmut, Houlston, Richard S., Morgan, Gareth J.
Published 2016

A molecular diagnostic approach able to detect the recurrent genetic prognostic factors typical of presenting myeloma

by Boyle, Eileen M, Proszek, Paula Z, Kaiser, Martin F, Begum, Dil, Dahir, Nasrin, Savola, Suvi, Wardell, Christopher P, Leleu, Xavier, Ross, Fiona M, Chiecchio, Laura, Cook, Gordon, Drayson, Mark T, Owen, Richard G, Ashcroft, John M, Jackson, Graham H, Anthony Child, James, Davies, Faith E, Walker, Brian A, Morgan, Gareth J
Published 2015

The CCND1 870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma

by Weinhold, Niels, Johnson, David C, Chubb, Daniel, Chen, Bowang, Försti, Asta, Hosking, Fay J, Broderick, Peter, Ma, Yussanne P, Dobbins, Sara E, Hose, Dirk, Walker, Brian A, Davies, Faith E, Kaiser, Martin F, Li, Ni L, Gregory, Walter A, Jackson, Graham H, Witzens-Harig, Mathias, Neben, Kai, Hoffmann, Per, Nöthen, Markus M, Mühleisen, Thomas W, Eisele, Lewin, Ross, Fiona M, Jauch, Anna, Goldschmidt, Hartmut, Houlston, Richard S, Morgan, Gareth J, Hemminki, Kari
Published 2013

Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk

by Chubb, Daniel, Weinhold, Niels, Broderick, Peter, Chen, Bowang, Johnson, David C, Försti, Asta, Vijayakrishnan, Jayaram, Migliorini, Gabriele, Dobbins, Sara E, Holroyd, Amy, Hose, Dirk, Walker, Brian A, Davies, Faith E, Gregory, Walter A, Jackson, Graham H, Irving, Julie A, Pratt, Guy, Fegan, Chris, Fenton, James AL, Neben, Kai, Hoffmann, Per, Nöthen, Markus M, Mühleisen, Thomas W, Eisele, Lewin, Ross, Fiona M, Straka, Christian, Einsele, Hermann, Langer, Christian, Dörner, Elisabeth, Allan, James M, Jauch, Anna, Morgan, Gareth J, Hemminki, Kari, Houlston, Richard S, Goldschmidt, Hartmut
Published 2013

Genome-wide association study identifies multiple susceptibility loci for multiple myeloma

by Mitchell, Jonathan S., Li, Ni, Weinhold, Niels, Försti, Asta, Ali, Mina, van Duin, Mark, Thorleifsson, Gudmar, Johnson, David C., Chen, Bowang, Halvarsson, Britt-Marie, Gudbjartsson, Daniel F., Kuiper, Rowan, Stephens, Owen W., Bertsch, Uta, Broderick, Peter, Campo, Chiara, Einsele, Hermann, Gregory, Walter A., Gullberg, Urban, Henrion, Marc, Hillengass, Jens, Hoffmann, Per, Jackson, Graham H., Johnsson, Ellinor, Jöud, Magnus, Kristinsson, Sigurður Y., Lenhoff, Stig, Lenive, Oleg, Mellqvist, Ulf-Henrik, Migliorini, Gabriele, Nahi, Hareth, Nelander, Sven, Nickel, Jolanta, Nöthen, Markus M., Rafnar, Thorunn, Ross, Fiona M., da Silva Filho, Miguel Inacio, Swaminathan, Bhairavi, Thomsen, Hauke, Turesson, Ingemar, Vangsted, Annette, Vogel, Ulla, Waage, Anders, Walker, Brian A., Wihlborg, Anna-Karin, Broyl, Annemiek, Davies, Faith E., Thorsteinsdottir, Unnur, Langer, Christian, Hansson, Markus, Kaiser, Martin, Sonneveld, Pieter, Stefansson, Kari, Morgan, Gareth J., Goldschmidt, Hartmut, Hemminki, Kari, Nilsson, Björn, Houlston, Richard S.
Published 2016