MED12 exon 2 mutations are common in uterine leiomyomas from South African patients

by Mäkinen, Netta, Heinonen, Hanna-Riikka, Moore, Shane, Tomlinson, Ian P.M., van der Spuy, Zephne M., Aaltonen, Lauri A.
Published 2011

What Can Be Learnt about Disease Progression in Breast Cancer Dormancy from Relapse Data?

by Willis, Lisa, Graham, Trevor A., Alarcón, Tomás, Alison, Malcolm R., Tomlinson, Ian P. M., Page, Karen M.
Published 2013

A Novel Test for Gene-Ancestry Interactions in Genome-Wide Association Data

by Davies, Joanna L., Cazier, Jean-Baptiste, Dunlop, Malcolm G., Houlston, Richard S., Tomlinson, Ian P., Holmes, Chris C.
Published 2012

Methylation changes in the TFAP2E promoter region are associated with BRAF mutation and poorer overall & disease free survival in colorectal cancer

by Beggs, Andrew D., Dilworth, Mark P., Domingo, Enric, Midgley, Rachel, Kerr, David, Tomlinson, Ian P.M., Middleton, Gary W.
Published 2015

Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression

by Schödel, Johannes, Bardella, Chiara, Sciesielski, Lina K, Brown, Jill M, Pugh, Chris W, Buckle, Veronica, Tomlinson, Ian P, Ratcliffe, Peter J, Mole, David R
Published 2012

Loss of Expression and Promoter Methylation of SLIT2 Are Associated with Sessile Serrated Adenoma Formation

by Beggs, Andrew D., Jones, Angela, Shepherd, Neil, Arnaout, Abed, Finlayson, Caroline, Abulafi, A. Muti, Morton, Dion G., Matthews, Glenn M., Hodgson, Shirley V., Tomlinson, Ian P. M.
Published 2013

A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts

by Leedham, Simon J, Rodenas-Cuadrado, Pedro, Howarth, Kimberley, Lewis, Annabelle, Mallappa, Sreelakshmi, Segditsas, Stefania, Davis, Hayley, Jeffery, Rosemary, Rodriguez-Justo, Manuel, Keshav, Satish, Travis, Simon P L, Graham, Trevor A, East, James, Clark, Susan, Tomlinson, Ian P M
Published 2013

DNA polymerase ɛ and δ exonuclease domain mutations in endometrial cancer

by Church, David N., Briggs, Sarah E.W., Palles, Claire, Domingo, Enric, Kearsey, Stephen J., Grimes, Jonathon M., Gorman, Maggie, Martin, Lynn, Howarth, Kimberley M., Hodgson, Shirley V., Kaur, Kulvinder, Taylor, Jenny, Tomlinson, Ian P.M.
Published 2013

Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia

by Papaemmanuil, Elli, Hosking, Fay J, Vijayakrishnan, Jayaram, Price, Amy, Olver, Bianca, Sheridan, Eammon, Kinsey, Sally E, Lightfoot, Tracy, Roman, Eve, Irving, Julie A E, Allan, James M., Tomlinson, Ian P, Taylor, Malcolm, Greaves, Mel, Houlston, Richard S
Published 2009

A colorectal cancer genome-wide association study in a Spanish cohort identifies two variants associated with colorectal cancer risk at 1p33 and 8p12

by Fernandez-Rozadilla, Ceres, Cazier, Jean-Baptiste, Tomlinson, Ian P, Carvajal-Carmona, Luis G, Palles, Claire, Lamas, María J, Baiget, Montserrat, López-Fernández, Luis A, Brea-Fernández, Alejandro, Abulí, Anna, Bujanda, Luis, Clofent, Juan, Gonzalez, Dolors, Xicola, Rosa, Andreu, Montserrat, Bessa, Xavier, Jover, Rodrigo, Llor, Xavier, Moreno, Víctor, Castells, Antoni, Carracedo, Ángel, Castellvi-Bel, Sergi, Ruiz-Ponte, Clara
Published 2013

Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk

by Broderick, Peter, Chubb, Daniel, Johnson, David C, Weinhold, Niels, Försti, Asta, Lloyd, Amy, Olver, Bianca, Ma, Yussanne, Dobbins, Sara E, Walker, Brian A, Davies, Faith E, Gregory, Walter A, Childs, J. Anthony, Ross, Fiona M, Jackson, Graham H, Neben, Kai, Jauch, Anna, Hoffmann, Per, Mühleisen, Thomas W, Nöthen, Markus M, Moebus, Susanne, Tomlinson, Ian P, Goldschmidt, Hartmut, Hemminki, Kari, Morgan, Gareth J, Houlston, Richard S
Published 2011

Replication stress links structural and numerical cancer chromosomal instability

by Burrell, Rebecca A., McClelland, Sarah E., Endesfelder, David, Groth, Petra, Weller, Marie-Christine, Shaikh, Nadeem, Domingo, Enric, Kanu, Nnennaya, Dewhurst, Sally M., Gronroos, Eva, Chew, Su Kit, Rowan, Andrew J., Schenk, Arne, Sheffer, Michal, Howell, Michael, Kschischo, Maik, Behrens, Axel, Helleday, Thomas, Bartek, Jiri, Tomlinson, Ian P., Swanton, Charles
Published 2013

Prognostic Significance of POLE Proofreading Mutations in Endometrial Cancer

by Church, David N., Stelloo, Ellen, Nout, Remi A., Valtcheva, Nadejda, Depreeuw, Jeroen, ter Haar, Natalja, Noske, Aurelia, Amant, Frederic, Tomlinson, Ian P. M., Wild, Peter J., Lambrechts, Diether, Jürgenliemk-Schulz, Ina M., Jobsen, Jan J., Smit, Vincent T. H. B. M., Creutzberg, Carien L., Bosse, Tjalling
Published 2014

Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13

by Spain, Sarah L., Carvajal-Carmona, Luis G., Howarth, Kimberley M., Jones, Angela M., Su, Zhan, Cazier, Jean-Baptiste, Williams, Jennet, Aaltonen, Lauri A., Pharoah, Paul, Kerr, David J., Cheadle, Jeremy, Li, Li, Casey, Graham, Vodicka, Pavel, Sieber, Oliver, Lipton, Lara, Gibbs, Peter, Martin, Nicholas G., Montgomery, Grant W., Young, Joanne, Baird, Paul N., Morreau, Hans, van Wezel, Tom, Ruiz-Ponte, Clara, Fernandez-Rozadilla, Ceres, Carracedo, Angel, Castells, Antoni, Castellvi-Bel, Sergi, Dunlop, Malcolm, Houlston, Richard S., Tomlinson, Ian P.M.
Published 2012

Erratum: A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer

by Al-Tassan, Nada A., Whiffin, Nicola, Hosking, Fay J., Palles, Claire, Farrington, Susan M., Dobbins, Sara E., Harris, Rebecca, Gorman, Maggie, Tenesa, Albert, Meyer, Brian F., Wakil, Salma M., Kinnersley, Ben, Campbell, Harry, Martin, Lynn, Smith, Christopher G., Idziaszczyk, Shelley, Barclay, Ella, Maughan, Timothy S., Kaplan, Richard, Kerr, Rachel, Kerr, David, Buchanan, Daniel D., Win, Aung Ko, Hopper, John, Jenkins, Mark, Lindor, Noralane M., Newcomb, Polly A., Gallinger, Steve, Conti, David, Schumacher, Fred, Casey, Graham, Dunlop, Malcolm G., Tomlinson, Ian P., Cheadle, Jeremy P., Houlston, Richard S.
Published 2015

A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer

by Al-Tassan, Nada A., Whiffin, Nicola, Hosking, Fay J., Palles, Claire, Farrington, Susan M., Dobbins, Sara E., Harris, Rebecca, Gorman, Maggie, Tenesa, Albert, Meyer, Brian F., Wakil, Salma M., Kinnersley, Ben, Campbell, Harry, Martin, Lynn, Smith, Christopher G., Idziaszczyk, Shelley, Barclay, Ella, Maughan, Timothy S., Kaplan, Richard, Kerr, Rachel, Kerr, David, Buchannan, Daniel D., Ko Win, Aung, Hopper, John, Jenkins, Mark, Lindor, Noralane M., Newcomb, Polly A., Gallinger, Steve, Conti, David, Schumacher, Fred, Casey, Graham, Dunlop, Malcolm G., Tomlinson, Ian P., Cheadle, Jeremy P., Houlston, Richard S.
Published 2015

Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer

by Tomlinson, Ian P. M., Carvajal-Carmona, Luis G., Dobbins, Sara E., Tenesa, Albert, Jones, Angela M., Howarth, Kimberley, Palles, Claire, Broderick, Peter, Jaeger, Emma E. M., Farrington, Susan, Lewis, Annabelle, Prendergast, James G. D., Pittman, Alan M., Theodoratou, Evropi, Olver, Bianca, Walker, Marion, Penegar, Steven, Barclay, Ella, Whiffin, Nicola, Martin, Lynn, Ballereau, Stephane, Lloyd, Amy, Gorman, Maggie, Lubbe, Steven, Howie, Bryan, Marchini, Jonathan, Ruiz-Ponte, Clara, Fernandez-Rozadilla, Ceres, Castells, Antoni, Carracedo, Angel, Castellvi-Bel, Sergi, Duggan, David, Conti, David, Cazier, Jean-Baptiste, Campbell, Harry, Sieber, Oliver, Lipton, Lara, Gibbs, Peter, Martin, Nicholas G., Montgomery, Grant W., Young, Joanne, Baird, Paul N., Gallinger, Steven, Newcomb, Polly, Hopper, John, Jenkins, Mark A., Aaltonen, Lauri A., Kerr, David J., Cheadle, Jeremy, Pharoah, Paul, Casey, Graham, Houlston, Richard S., Dunlop, Malcolm G.
Published 2011

Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease

by Orlando, Giulia, Law, Philip J., Palin, Kimmo, Tuupanen, Sari, Gylfe, Alexandra, Hänninen, Ulrika A., Cajuso, Tatiana, Tanskanen, Tomas, Kondelin, Johanna, Kaasinen, Eevi, Sarin, Antti-Pekka, Kaprio, Jaakko, Eriksson, Johan G., Rissanen, Harri, Knekt, Paul, Pukkala, Eero, Jousilahti, Pekka, Salomaa, Veikko, Ripatti, Samuli, Palotie, Aarno, Järvinen, Heikki, Renkonen-Sinisalo, Laura, Lepistö, Anna, Böhm, Jan, Mecklin, Jukka-Pekka, Al-Tassan, Nada A., Palles, Claire, Martin, Lynn, Barclay, Ella, Tenesa, Albert, Farrington, Susan, Timofeeva, Maria N., Meyer, Brian F., Wakil, Salma M., Campbell, Harry, Smith, Christopher G., Idziaszczyk, Shelley, Maughan, Timothy S., Kaplan, Richard, Kerr, Rachel, Kerr, David, Buchanan, Daniel D., Ko Win, Aung, Hopper, John, Jenkins, Mark, Lindor, Noralane M., Newcomb, Polly A., Gallinger, Steve, Conti, David, Schumacher, Fred, Casey, Graham, Taipale, Jussi, Cheadle, Jeremy P., Dunlop, Malcolm G., Tomlinson, Ian P., Aaltonen, Lauri A., Houlston, Richard S.
Published 2016

Recurrent Coding Sequence Variation Explains Only A Small Fraction of the Genetic Architecture of Colorectal Cancer

by Timofeeva, Maria N., Kinnersley, Ben, Farrington, Susan M., Whiffin, Nicola, Palles, Claire, Svinti, Victoria, Lloyd, Amy, Gorman, Maggie, Ooi, Li-Yin, Hosking, Fay, Barclay, Ella, Zgaga, Lina, Dobbins, Sara, Martin, Lynn, Theodoratou, Evropi, Broderick, Peter, Tenesa, Albert, Smillie, Claire, Grimes, Graeme, Hayward, Caroline, Campbell, Archie, Porteous, David, Deary, Ian J., Harris, Sarah E., Northwood, Emma L., Barrett, Jennifer H., Smith, Gillian, Wolf, Roland, Forman, David, Morreau, Hans, Ruano, Dina, Tops, Carli, Wijnen, Juul, Schrumpf, Melanie, Boot, Arnoud, Vasen, Hans F A, Hes, Frederik J., van Wezel, Tom, Franke, Andre, Lieb, Wolgang, Schafmayer, Clemens, Hampe, Jochen, Buch, Stephan, Propping, Peter, Hemminki, Kari, Försti, Asta, Westers, Helga, Hofstra, Robert, Pinheiro, Manuela, Pinto, Carla, Teixeira, Manuel, Ruiz-Ponte, Clara, Fernández-Rozadilla, Ceres, Carracedo, Angel, Castells, Antoni, Castellví-Bel, Sergi, Campbell, Harry, Bishop, D. Timothy, Tomlinson, Ian P M, Dunlop, Malcolm G., Houlston, Richard S.
Published 2015

Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer

by Jarvis, David, Mitchell, Jonathan S, Law, Philip J, Palin, Kimmo, Tuupanen, Sari, Gylfe, Alexandra, Hänninen, Ulrika A, Cajuso, Tatiana, Tanskanen, Tomas, Kondelin, Johanna, Kaasinen, Eevi, Sarin, Antti-Pekka, Kaprio, Jaakko, Eriksson, Johan G, Rissanen, Harri, Knekt, Paul, Pukkala, Eero, Jousilahti, Pekka, Salomaa, Veikko, Ripatti, Samuli, Palotie, Aarno, Järvinen, Heikki, Renkonen-Sinisalo, Laura, Lepistö, Anna, Böhm, Jan, Meklin, Jukka-Pekka, Al-Tassan, Nada A, Palles, Claire, Martin, Lynn, Barclay, Ella, Farrington, Susan M, Timofeeva, Maria N, Meyer, Brian F, Wakil, Salma M, Campbell, Harry, Smith, Christopher G, Idziaszczyk, Shelley, Maughan, Timothy S, Kaplan, Richard, Kerr, Rachel, Kerr, David, Buchanan, Daniel D, Win, Aung K, Hopper, John L, Jenkins, Mark A, Lindor, Noralane M, Newcomb, Polly A, Gallinger, Steve, Conti, David, Schumacher, Fred, Casey, Graham, Taipale, Jussi, Aaltonen, Lauri A, Cheadle, Jeremy P, Dunlop, Malcolm G, Tomlinson, Ian P, Houlston, Richard S
Published 2016