A stressful life (or death): Combinatorial proteotoxic approaches to cancer-selective therapeutic vulnerability

by Workman, Paul, Davies, Faith E.
Published 2011

Bortezomib (Velcade™) in the Treatment of Multiple Myeloma

by Field-Smith, Antonia, Morgan, Gareth J, Davies, Faith E
Published 2006

Inhibiting the molecular evolution of cancer through HSP90

by Martins, Ana Sofia, Davies, Faith E, Workman, Paul
Published 2012

Heat shock proteins in multiple myeloma

by Zhang, Lei, Fok, Jacqueline H.L., Davies, Faith E.
Published 2014

Mapping EORTC QLQ-C30 and QLQ-MY20 to EQ-5D in patients with multiple myeloma

by Proskorovsky, Irina, Lewis, Philip, Williams, Cathy D, Jordan, Karin, Kyriakou, Charalampia, Ishak, Jack, Davies, Faith E
Published 2014

Cleavage of BLOC1S1 mRNA by IRE1 Is Sequence Specific, Temporally Separate from XBP1 Splicing, and Dispensable for Cell Viability under Acute Endoplasmic Reticulum Stress

by Bright, Michael D., Itzhak, Daniel N., Wardell, Christopher P., Morgan, Gareth J., Davies, Faith E.
Published 2015

Hsp70 inhibition induces myeloma cell death via the intracellular accumulation of immunoglobulin and the generation of proteotoxic stress☆

by Zhang, Lei, Fok, Jacqueline J.L., Mirabella, Fabio, Aronson, Lauren I., Fryer, Rosemary A., Workman, Paul, Morgan, Gareth J., Davies, Faith E.
Published 2013

Effect of general symptom level, specific adverse events, treatment patterns, and patient characteristics on health-related quality of life in patients with multiple myeloma: resul...

by Jordan, Karin, Proskorovsky, Irina, Lewis, Philip, Ishak, Jack, Payne, Krista, Lordan, Noreen, Kyriakou, Charalampia, Williams, Cathy D., Peters, Sarah, Davies, Faith E.
Published 2013

Characterization of a Novel Mouse Model of Multiple Myeloma and Its Use in Preclinical Therapeutic Assessment

by Fryer, Rosemary A., Graham, Timothy J., Smith, Emma M., Walker-Samuel, Simon, Morgan, Gareth J., Robinson, Simon P., Davies, Faith E.
Published 2013

Implementation of genome-wide complex trait analysis to quantify the heritability in multiple myeloma

by Mitchell, Jonathan S., Johnson, David C., Litchfield, Kevin, Broderick, Peter, Weinhold, Niels, Davies, Faith E., Gregory, Walter A., Jackson, Graham H., Kaiser, Martin, Morgan, Gareth J., Houlston, Richard S.
Published 2015

The combination of HDAC and aminopeptidase inhibitors is highly synergistic in myeloma and leads to disruption of the NFκB signalling pathway

by Smith, Emma M., Zhang, Lei, Walker, Brian A., Davenport, Emma L., Aronson, Lauren I., Krige, David, Hooftman, Leon, Drummond, Alan H., Morgan, Gareth J., Davies, Faith E.
Published 2013

A Novel Functional Role for MMSET in RNA Processing Based on the Link Between the REIIBP Isoform and Its Interaction with the SMN Complex

by Mirabella, Fabio, Murison, Alexander, Aronson, Lauren I., Wardell, Christopher P., Thompson, Andrew J., Hanrahan, Sarah J., Fok, Jacqueline H. L., Pawlyn, Charlotte, Kaiser, Martin F., Walker, Brian A., Davies, Faith E., Morgan, Gareth J.
Published 2014

A gene expression based predictor for high risk myeloma treated with intensive therapy and autologous stem cell rescue

by Wu, Ping, Walker, Brian A., Broyl, Annemiek, Kaiser, Martin, Johnson, David C., Kuiper, Rowan, van Duin, Mark, Gregory, Walter M., Davies, Faith E., Brewer, Daniel, Hose, Dirk, Sonneveld, Pieter, Morgan, Gareth J.
Published 2015

Effects of zoledronic acid versus clodronic acid on skeletal morbidity in patients with newly diagnosed multiple myeloma (MRC Myeloma IX): secondary outcomes from a randomised cont...

by Morgan, Gareth J, Child, J Anthony, Gregory, Walter M, Szubert, Alex J, Cocks, Kim, Bell, Sue E, Navarro-Coy, Nuria, Drayson, Mark T, Owen, Roger G, Feyler, Sylvia, Ashcroft, A John, Ross, Fiona M, Byrne, Jennifer, Roddie, Huw, Rudin, Claudius, Cook, Gordon, Jackson, Graham H, Wu, Ping, Davies, Faith E
Published 2011

First-line treatment with zoledronic acid as compared with clodronic acid in multiple myeloma (MRC Myeloma IX): a randomised controlled trial

by Morgan, Gareth J, Davies, Faith E, Gregory, Walter M, Cocks, Kim, Bell, Sue E, Szubert, Alex J, Navarro-Coy, Nuria, Drayson, Mark T, Owen, Roger G, Feyler, Sylvia, Ashcroft, A John, Ross, Fiona, Byrne, Jennifer, Roddie, Huw, Rudin, Claudius, Cook, Gordon, Jackson, Graham H, Child, J Anthony
Published 2010

Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms

by Walker, Brian A, Wardell, Christopher P, Melchor, Lorenzo, Brioli, Annamaria, Johnson, David C, Kaiser, Martin F, Mirabella, Fabio, Lopez-Corral, Lucia, Humphray, Sean, Murray, Lisa, Ross, Mark, Bentley, David, Gutiérrez, Norma C., Garcia-Sanz, Ramón, San Miguel, Jesus, Davies, Faith E, Gonzalez, David, Morgan, Gareth J
Published 2013

A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial

by Boyd, Kevin D, Ross, Fiona M, Chiecchio, Laura, Dagrada, GianPaolo, Konn, Zoe J, Tapper, William J, Walker, Brian A, Wardell, Christopher P, Gregory, Walter M, Szubert, Alex J, Bell, Sue E, Child, J Anthony, Jackson, Graham H, Davies, Faith E, Morgan, Gareth J
Published 2011

Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk

by Broderick, Peter, Chubb, Daniel, Johnson, David C, Weinhold, Niels, Försti, Asta, Lloyd, Amy, Olver, Bianca, Ma, Yussanne, Dobbins, Sara E, Walker, Brian A, Davies, Faith E, Gregory, Walter A, Childs, J. Anthony, Ross, Fiona M, Jackson, Graham H, Neben, Kai, Jauch, Anna, Hoffmann, Per, Mühleisen, Thomas W, Nöthen, Markus M, Moebus, Susanne, Tomlinson, Ian P, Goldschmidt, Hartmut, Hemminki, Kari, Morgan, Gareth J, Houlston, Richard S
Published 2011

APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma

by Walker, Brian A, Wardell, Christopher P, Murison, Alex, Boyle, Eileen M, Begum, Dil B, Dahir, Nasrin M, Proszek, Paula Z, Melchor, Lorenzo, Pawlyn, Charlotte, Kaiser, Martin F, Johnson, David C, Qiang, Ya-Wei, Jones, John R, Cairns, David A, Gregory, Walter M, Owen, Roger G, Cook, Gordon, Drayson, Mark T, Jackson, Graham H, Davies, Faith E, Morgan, Gareth J
Published 2015

A molecular diagnostic approach able to detect the recurrent genetic prognostic factors typical of presenting myeloma

by Boyle, Eileen M, Proszek, Paula Z, Kaiser, Martin F, Begum, Dil, Dahir, Nasrin, Savola, Suvi, Wardell, Christopher P, Leleu, Xavier, Ross, Fiona M, Chiecchio, Laura, Cook, Gordon, Drayson, Mark T, Owen, Richard G, Ashcroft, John M, Jackson, Graham H, Anthony Child, James, Davies, Faith E, Walker, Brian A, Morgan, Gareth J
Published 2015