Mechanism of Generation of Therapy Related Leukemia in Response to Anti-Topoisomerase II Agents

by Cowell, Ian G., Austin, Caroline A.
Published 2012

Do transcription factories and TOP2B provide a recipe for chromosome translocations in therapy-related leukemia?

by Cowell, Ian G., Austin, Caroline A.
Published 2012

Myeloperoxidase Enhances Etoposide and Mitoxantrone-Mediated DNA Damage: A Target for Myeloprotection in Cancer Chemotherapy

by Atwal, Mandeep, Lishman, Emma L., Austin, Caroline A., Cowell, Ian G.
Published 2017

Proteasomal inhibition potentiates drugs targeting DNA topoisomerase II

by Lee, Ka C., Bramley, Rebecca L., Cowell, Ian G., Jackson, Graham H., Austin, Caroline A.
Published 2016

γH2AX Foci Form Preferentially in Euchromatin after Ionising-Radiation

by Cowell, Ian G., Sunter, Nicola J., Singh, Prim B., Austin, Caroline A., Durkacz, Barbara W., Tilby, Michael J.
Published 2007

Genome-wide ChIP-seq analysis of human TOP2B occupancy in MCF7 breast cancer epithelial cells

by Manville, Catriona M., Smith, Kayleigh, Sondka, Zbyslaw, Rance, Holly, Cockell, Simon, Cowell, Ian G., Lee, Ka Cheong, Morris, Nicholas J., Padget, Kay, Jackson, Graham H., Austin, Caroline A.
Published 2015

MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA

by Lee, Ka Cheong, Padget, Kay, Curtis, Hannah, Cowell, Ian G., Moiani, Davide, Sondka, Zbyslaw, Morris, Nicholas J., Jackson, Graham H., Cockell, Simon J., Tainer, John A., Austin, Caroline A.
Published 2012

Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons

by Best, Andrew, James, Katherine, Dalgliesh, Caroline, Hong, Elaine, Kheirolahi-Kouhestani, Mahsa, Curk, Tomaz, Xu, Yaobo, Danilenko, Marina, Hussain, Rafiq, Keavney, Bernard, Wipat, Anil, Klinck, Roscoe, Cowell, Ian G., Cheong Lee, Ka, Austin, Caroline A., Venables, Julian P., Chabot, Benoit, Santibanez Koref, Mauro, Tyson-Capper, Alison, Elliott, David J.
Published 2014