Chromosomal rearrangements in cancer: Detection and potential causal mechanisms

by Hasty, Paul, Montagna, Cristina
Published 2014

p53 as an intervention target for cancer and aging

by Hasty, Paul, Christy, Barbara A.
Published 2013

Non-homologous end joining, but not homologous recombination, enables survival for cells exposed to a histone deacetylase inhibitor

by Yaneva, Mariana, Li, Han, Marple, Teresa, Hasty, Paul
Published 2005

Biochemical and cellular characteristics of the 3′ → 5′ exonuclease TREX2

by Chen, Ming-Jiu, Ma, Sheng-Mei, Dumitrache, Lavinia C., Hasty, Paul
Published 2007

High Preservation of CpG Cytosine Methylation Patterns at Imprinted Gene Loci in Liver and Brain of Aged Mice

by Gravina, Silvia, Dollé, Martijn E. T., Wang, Tao, van Steeg, Harry, Hasty, Paul, Hoeijmakers, Jan, Vijg, Jan
Published 2013

RECQL5 and BLM exhibit divergent functions in cells defective for the Fanconi anemia pathway

by Kim, Tae Moon, Son, Mi Young, Dodds, Sherry, Hu, Lingchuan, Luo, Guangbin, Hasty, Paul
Published 2015

Potential Relationship between Inadequate Response to DNA Damage and Development of Myelodysplastic Syndrome

by Zhou, Ting, Chen, Peishuai, Gu, Jian, Bishop, Alexander J. R., Scott, Linda M., Hasty, Paul, Rebel, Vivienne I.
Published 2015

Adaptations to chronic rapamycin in mice

by Dodds, Sherry G., Livi, Carolina B., Parihar, Manish, Hsu, Hang-Kai, Benavides, Adriana D., Morris, Jay, Javors, Martin, Strong, Randy, Christy, Barbara, Hasty, Paul, Sharp, Zelton Dave
Published 2016

Adaptive Stress Response in Segmental Progeria Resembles Long-Lived Dwarfism and Calorie Restriction in Mice

by van de Ven, Marieke, Andressoo, Jaan-Olle, Holcomb, Valerie B, von Lindern, Marieke, Jong, Willeke M. C, Zeeuw, Chris I. De, Suh, Yousin, Hasty, Paul, Hoeijmakers, Jan H. J, van der Horst, Gijsbertus T. J, Mitchell, James R
Published 2006

Rapamycin extends life span of Rb1+/− mice by inhibiting neuroendocrine tumors

by Livi, Carolina B., Hardman, Rulon L., Christy, Barbara A., Dodds, Sherry G., Jones, Diane, Williams, Charnae, Strong, Randy, Bokov, Alex, Javors, Martin A., Ikeno, Yuji, Hubbard, Gene, Hasty, Paul, Sharp, Zelton Dave
Published 2013

The Progeroid Phenotype of Ku80 Deficiency Is Dominant over DNA-PKCS Deficiency

by Reiling, Erwin, Dollé, Martijn E. T., Youssef, Sameh A., Lee, Moonsook, Nagarajah, Bhawani, Roodbergen, Marianne, de With, Piet, de Bruin, Alain, Hoeijmakers, Jan H., Vijg, Jan, van Steeg, Harry, Hasty, Paul
Published 2014

Deletion of Individual Ku Subunits in Mice Causes an NHEJ-Independent Phenotype Potentially by Altering Apurinic/Apyrimidinic Site Repair

by Choi, Yong Jun, Li, Han, Son, Mi Young, Wang, Xiao-hong, Fornsaglio, Jamie L., Sobol, Robert W., Lee, Moonsook, Vijg, Jan, Imholz, Sandra, Dollé, Martijn E. T., van Steeg, Harry, Reiling, Erwin, Hasty, Paul
Published 2014

Two Replication Fork Maintenance Pathways Fuse Inverted Repeats to Rearrange Chromosomes

by Hu, Lingchuan, Kim, Tae Moon, Son, Mi Young, Kim, Sung-A, Holland, Cory L., Tateishi, Satoshi, Kim, Dong Hyun, Yew, P. Renee, Montagna, Cristina, Dumitrache, Lavinia C., Hasty, Paul
Published 2013

Chronic mTOR inhibition in mice with rapamycin alters T, B, myeloid, and innate lymphoid cells and gut flora and prolongs life of immune‐deficient mice

by Hurez, Vincent, Dao, Vinh, Liu, Aijie, Pandeswara, Srilakshmi, Gelfond, Jonathan, Sun, Lishi, Bergman, Molly, Orihuela, Carlos J., Galvan, Veronica, Padrón, Álvaro, Drerup, Justin, Liu, Yang, Hasty, Paul, Sharp, Zelton Dave, Curiel, Tyler J.
Published 2015

p53 and rapamycin are additive

by Christy, Barbara, Demaria, Marco, Campisi, Judith, Huang, Jing, Jones, Diane, Dodds, Sherry G., Williams, Charnae, Hubbard, Gene, Livi, Carolina B., Gao, Xiaoli, Weintraub, Susan, Curiel, Tyler, Sharp, Z. Dave, Hasty, Paul
Published 2015

Broad segmental progeroid changes in short-lived Ercc1−/Δ7 mice

by Dollé, Martijn E.T., Kuiper, Raoul V., Roodbergen, Marianne, Robinson, Joke, de Vlugt, Sisca, Wijnhoven, Susan W.P., Beems, Rudolf B., de la Fonteyne, Liset, de With, Piet, van der Pluijm, Ingrid, Niedernhofer, Laura J., Hasty, Paul, Vijg, Jan, Hoeijmakers, Jan H.J., van Steeg, Harry
Published 2011