Potential Relationship between Inadequate Response to DNA Damage and Development of Myelodysplastic Syndrome

Hematopoietic stem cells (HSCs) are responsible for the continuous regeneration of all types of blood cells, including themselves. To ensure the functional and genomic integrity of blood tissue, a network of regulatory pathways tightly controls the proliferative status of HSCs. Nevertheless, normal...

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Bibliographic Details
Main Authors: Zhou, Ting, Chen, Peishuai, Gu, Jian, Bishop, Alexander J. R., Scott, Linda M., Hasty, Paul, Rebel, Vivienne I.
Format: Online
Language:English
Published: MDPI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307285/