Potential Relationship between Inadequate Response to DNA Damage and Development of Myelodysplastic Syndrome
Hematopoietic stem cells (HSCs) are responsible for the continuous regeneration of all types of blood cells, including themselves. To ensure the functional and genomic integrity of blood tissue, a network of regulatory pathways tightly controls the proliferative status of HSCs. Nevertheless, normal...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
MDPI
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307285/ |