RACK1, A multifaceted scaffolding protein: Structure and function

by Adams, David R, Ron, Dorit, Kiely, Patrick A
Published 2011

RACK(1) to the future – a historical perspective

by Ron, Dorit, Adams, David R, Baillie, George S, Long, Aideen, O’Connor, Rosemary, Kiely, Patrick A
Published 2013

Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs

by Hudson, Brian D., Christiansen, Elisabeth, Tikhonova, Irina G., Grundmann, Manuel, Kostenis, Evi, Adams, David R., Ulven, Trond, Milligan, Graeme
Published 2012

Limited Effects of Endurance or Interval Training on Visceral Adipose Tissue and Systemic Inflammation in Sedentary Middle-Aged Men

by Cooper, Joshua H. F., Collins, Blake E. G., Adams, David R., Robergs, Robert A., Donges, Cheyne E.
Published 2016

Genomewide significance testing of variation from single case exomes

by Wilfert, Amy B., Chao, Katherine R., Kaushal, Madhurima, Jain, Sanjay, Zöllner, Sebastian, Adams, David R., Conrad, Donald F.
Published 2016

The Undiagnosed Diseases Program Integrated Collaboration System (UDPICS): One Program’s Experience Developing Custom Software to Support Research for Complex-Disease Families

by Guzman, Jessica, Lee, Elizabeth, Draper, David, Valivullah, Zaheer, Yu, Guoyun, Sincan, Murat, Gahl, William A., Adams, David R.
Published 2015

Chemical informatics uncovers a new role for moexipril as a novel inhibitor of cAMP phosphodiesterase-4 (PDE4)

by Cameron, Ryan T., Coleman, Ryan G., Day, Jon P., Yalla, Krishna C., Houslay, Miles D., Adams, David R., Shoichet, Brian K., Baillie, George S.
Published 2013

A patient with multisystem dysfunction carries a truncation mutation in human SLC12A2, the gene encoding the Na-K-2Cl cotransporter, NKCC1

by Delpire, Eric, Wolfe, Lynne, Flores, Bianca, Koumangoye, Rainelli, Schornak, Cara C., Omer, Salma, Pusey, Barbara, Lau, Christopher, Markello, Thomas, Adams, David R.
Published 2016

Explorations to improve the completeness of exome sequencing

by Du, Chen, Pusey, Barbara N., Adams, Christopher J., Lau, C. Christopher, Bone, William P., Gahl, William A., Markello, Thomas C., Adams, David R.
Published 2016

Replicate exome-sequencing in a multiple-generation family: improved interpretation of next-generation sequencing data

by Cherukuri, Praveen F., Maduro, Valerie, Fuentes-Fajardo, Karin V., Lam, Kevin, Adams, David R., Tifft, Cynthia J., Mullikin, James C., Gahl, William A., Boerkoel, Cornelius F.
Published 2015

Dimerization of cAMP phosphodiesterase-4 (PDE4) in living cells requires interfaces located in both the UCR1 and catalytic unit domains

by Bolger, Graeme B., Dunlop, Allan J., Meng, Dong, Day, Jon P., Klussmann, Enno, Baillie, George S., Adams, David R., Houslay, Miles D.
Published 2015

Functional Analysis of a De Novo GRIN2A Missense Mutation Associated with Early-onset Epileptic Encephalopathy

by Yuan, Hongjie, Hansen, Kasper B., Zhang, Jing, Pierson, Tyler Mark, Markello, Thomas C., Fuentes Fajardo, Karin V., Holloman, Conisha M., Golas, Gretchen, Adams, David R., Boerkoel, Cornelius F., Gahl, William A., Traynelis, Stephen F.
Published 2014

Pharmacogenomic incidental findings in 308 families: The NIH Undiagnosed Disease Program experience

by Lee, Elizabeth M.J., Xu, Karen, Mosbrook, Emma, Links, Amanda, Guzman, Jessica, Adams, David R., Flynn, Elise, Valkanas, Elise, Toro, Camillo, Tifft, Cynthia J., Boerkoel, Cornelius F., Gahl, William A., Sincan, Murat
Published 2016

The implications of familial incidental findings from exome sequencing: The NIH Undiagnosed Diseases Program experience

by Lawrence, Lauren, Sincan, Murat, Markello, Thomas, Adams, David R, Gill, Fred, Godfrey, Rena, Golas, Gretchen, Groden, Catherine, Landis, Dennis, Nehrebecky, Michele, Park, Grace, Soldatos, Ariane, Tifft, Cynthia, Toro, Camilo, Wahl, Colleen, Wolfe, Lynne, Gahl, William A., Boerkoel, Cornelius F.
Published 2014

GRIN2A mutation and early-onset epileptic encephalopathy: personalized therapy with memantine

by Pierson, Tyler Mark, Yuan, Hongjie, Marsh, Eric D, Fuentes-Fajardo, Karin, Adams, David R, Markello, Thomas, Golas, Gretchen, Simeonov, Dimitre R, Holloman, Conisha, Tankovic, Anel, Karamchandani, Manish M, Schreiber, John M, Mullikin, James C, Tifft, Cynthia J, Toro, Camilo, Boerkoel, Cornelius F, Traynelis, Stephen F, Gahl, William A
Published 2014

Complex translocation disrupting TCF4 and altering TCF4 isoform expression segregates as mild autosomal dominant intellectual disability

by Maduro, Valerie, Pusey, Barbara N., Cherukuri, Praveen F., Atkins, Paul, du Souich, Christèle, Rupps, Rosemarie, Limbos, Marjolaine, Adams, David R., Bhatt, Samarth S., Eydoux, Patrice, Links, Amanda E., Lehman, Anna, Malicdan, May C., Mason, Christopher E., Morimoto, Marie, Mullikin, James C., Sear, Andrew, Van Karnebeek, Clara, Stankiewicz, Pawel, Gahl, William A., Toro, Camilo, Boerkoel, Cornelius F.
Published 2016

Impaired osteoblast and osteoclast function characterize the osteoporosis of Snyder - Robinson syndrome

by Albert, Jessica S, Bhattacharyya, Nisan, Wolfe, Lynne A, Bone, William P, Maduro, Valerie, Accardi, John, Adams, David R, Schwartz, Charles E, Norris, Joy, Wood, Tim, Gafni, Rachel I, Collins, Michael T, Tosi, Laura L, Markello, Thomas C, Gahl, William A, Boerkoel, Cornelius F
Published 2015

Computational evaluation of exome sequence data using human and model organism phenotypes improves diagnostic efficiency

by Bone, William P., Washington, Nicole L., Buske, Orion J., Adams, David R., Davis, Joie, Draper, David, Flynn, Elise D., Girdea, Marta, Godfrey, Rena, Golas, Gretchen, Groden, Catherine, Jacobsen, Julius, Köhler, Sebastian, Lee, Elizabeth M. J., Links, Amanda E., Markello, Thomas C., Mungall, Christopher J., Nehrebecky, Michele, Robinson, Peter N., Sincan, Murat, Soldatos, Ariane G., Tifft, Cynthia J., Toro, Camilo, Trang, Heather, Valkanas, Elise, Vasilevsky, Nicole, Wahl, Colleen, Wolfe, Lynne A., Boerkoel, Cornelius F., Brudno, Michael, Haendel, Melissa A., Gahl, William A., Smedley, Damian
Published 2016