Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets

by Ulven, Trond
Published 2012

Comprehensive and quantitative profiling of lipid species in human milk, cow milk and a phospholipid-enriched milk formula by GC and MS/MSALL

by Sokol, Elena, Ulven, Trond, Færgeman, Nils J, Ejsing, Christer S
Published 2015

The Molecular Basis of Ligand Interaction at Free Fatty Acid Receptor 4 (FFA4/GPR120)*

by Hudson, Brian D., Shimpukade, Bharat, Milligan, Graeme, Ulven, Trond
Published 2014

Treatment of Type 2 Diabetes by Free Fatty Acid Receptor Agonists

by Watterson, Kenneth R., Hudson, Brian D., Ulven, Trond, Milligan, Graeme
Published 2014

Extracellular Ionic Locks Determine Variation in Constitutive Activity and Ligand Potency between Species Orthologs of the Free Fatty Acid Receptors FFA2 and FFA3*

by Hudson, Brian D., Tikhonova, Irina G., Pandey, Sunil K., Ulven, Trond, Milligan, Graeme
Published 2012

Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation

by Uller, Lena, Mathiesen, Jesper Mosolff, Alenmyr, Lisa, Korsgren, Magnus, Ulven, Trond, Högberg, Thomas, Andersson, Gunnar, Persson, Carl GA, Kostenis, Evi
Published 2007

Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs

by Hudson, Brian D., Christiansen, Elisabeth, Tikhonova, Irina G., Grundmann, Manuel, Kostenis, Evi, Adams, David R., Ulven, Trond, Milligan, Graeme
Published 2012

Non-equivalence of Key Positively Charged Residues of the Free Fatty Acid 2 Receptor in the Recognition and Function of Agonist Versus Antagonist Ligands*

by Sergeev, Eugenia, Hansen, Anders Højgaard, Pandey, Sunil K., MacKenzie, Amanda E., Hudson, Brian D., Ulven, Trond, Milligan, Graeme
Published 2016

Concomitant Action of Structural Elements and Receptor Phosphorylation Determines Arrestin-3 Interaction with the Free Fatty Acid Receptor FFA4*

by Butcher, Adrian J., Hudson, Brian D., Shimpukade, Bharat, Alvarez-Curto, Elisa, Prihandoko, Rudi, Ulven, Trond, Milligan, Graeme, Tobin, Andrew B.
Published 2014

PGH1, the Precursor for the Anti-Inflammatory Prostaglandins of the 1-series, Is a Potent Activator of the Pro-Inflammatory Receptor CRTH2/DP2

by Schröder, Ralf, Xue, Luzheng, Konya, Viktoria, Martini, Lene, Kampitsch, Nora, Whistler, Jennifer L., Ulven, Trond, Heinemann, Akos, Pettipher, Roy, Kostenis, Evi
Published 2012

Selective Orthosteric Free Fatty Acid Receptor 2 (FFA2) Agonists: IDENTIFICATION OF THE STRUCTURAL AND CHEMICAL REQUIREMENTS FOR SELECTIVE ACTIVATION OF FFA2 VERSUS FFA3*

by Schmidt, Johannes, Smith, Nicola J., Christiansen, Elisabeth, Tikhonova, Irina G., Grundmann, Manuel, Hudson, Brian D., Ward, Richard J., Drewke, Christel, Milligan, Graeme, Kostenis, Evi, Ulven, Trond
Published 2011

Reevaluation of Fatty Acid Receptor 1 as a Drug Target for the Stimulation of Insulin Secretion in Humans

by Wagner, Robert, Kaiser, Gabriele, Gerst, Felicia, Christiansen, Elisabeth, Due-Hansen, Maria E., Grundmann, Manuel, Machicao, Fausto, Peter, Andreas, Kostenis, Evi, Ulven, Trond, Fritsche, Andreas, Häring, Hans-Ulrich, Ullrich, Susanne
Published 2013

Discovery of TUG-770: A Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 Diabetes

by Christiansen, Elisabeth, Hansen, Steffen V. F., Urban, Christian, Hudson, Brian D., Wargent, Edward T., Grundmann, Manuel, Jenkins, Laura, Zaibi, Mohamed, Stocker, Claire J., Ullrich, Susanne, Kostenis, Evi, Kassack, Matthias U., Milligan, Graeme, Cawthorne, Michael A., Ulven, Trond
Published 2013

Defining the Molecular Basis for the First Potent and Selective Orthosteric Agonists of the FFA2 Free Fatty Acid Receptor*

by Hudson, Brian D., Due-Hansen, Maria E., Christiansen, Elisabeth, Hansen, Anna Mette, Mackenzie, Amanda E., Murdoch, Hannah, Pandey, Sunil K., Ward, Richard J., Marquez, Rudi, Tikhonova, Irina G., Ulven, Trond, Milligan, Graeme
Published 2013