Structure of the germline genome of Tetrahymena thermophila and relationship to the massively rearranged somatic genome

The germline genome of the binucleated ciliate Tetrahymena thermophila undergoes programmed chromosome breakage and massive DNA elimination to generate the somatic genome. Here, we present a complete sequence assembly of the germline genome and analyze multiple features of its structure and its rela...

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Bibliographic Details
Main Authors: Hamilton, Eileen P, Kapusta, Aurélie, Huvos, Piroska E, Bidwell, Shelby L, Zafar, Nikhat, Tang, Haibao, Hadjithomas, Michalis, Krishnakumar, Vivek, Badger, Jonathan H, Caler, Elisabet V, Russ, Carsten, Zeng, Qiandong, Fan, Lin, Levin, Joshua Z, Shea, Terrance, Young, Sarah K, Hegarty, Ryan, Daza, Riza, Gujja, Sharvari, Wortman, Jennifer R, Birren, Bruce W, Nusbaum, Chad, Thomas, Jainy, Carey, Clayton M, Pritham, Ellen J, Feschotte, Cédric, Noto, Tomoko, Mochizuki, Kazufumi, Papazyan, Romeo, Taverna, Sean D, Dear, Paul H, Cassidy-Hanley, Donna M, Xiong, Jie, Miao, Wei, Orias, Eduardo, Coyne, Robert S
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5182062/