RAB43 facilitates cross-presentation of cell-associated antigens by CD8α+ dendritic cells
RAB43 is a vesicular transport protein unique to CD8α+ DCs that is localized to the Golgi. Kretzer et al. show that RAB43 is necessary for optimal cross-presentation of cell-associated antigens by CD8α+ DCs in vitro and in vivo but that it is dispensable for cross-presentation by in vitro monocyte-d...
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| Format: | Online |
| Language: | English |
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The Rockefeller University Press
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154939/ |
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pubmed-5154939 |
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oai_dc |
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pubmed-51549392017-06-12 RAB43 facilitates cross-presentation of cell-associated antigens by CD8α+ dendritic cells Kretzer, Nicole M. Theisen, Derek J. Tussiwand, Roxane Briseño, Carlos G. Grajales-Reyes, Gary E. Wu, Xiaodi Durai, Vivek Albring, Jörn Bagadia, Prachi Murphy, Theresa L. Murphy, Kenneth M. Research Articles RAB43 is a vesicular transport protein unique to CD8α+ DCs that is localized to the Golgi. Kretzer et al. show that RAB43 is necessary for optimal cross-presentation of cell-associated antigens by CD8α+ DCs in vitro and in vivo but that it is dispensable for cross-presentation by in vitro monocyte-derived DCs. The Rockefeller University Press 2016-12-12 /pmc/articles/PMC5154939/ /pubmed/27899443 http://dx.doi.org/10.1084/jem.20160597 Text en © 2016 Kretzer et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/). |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Kretzer, Nicole M. Theisen, Derek J. Tussiwand, Roxane Briseño, Carlos G. Grajales-Reyes, Gary E. Wu, Xiaodi Durai, Vivek Albring, Jörn Bagadia, Prachi Murphy, Theresa L. Murphy, Kenneth M. |
| spellingShingle |
Kretzer, Nicole M. Theisen, Derek J. Tussiwand, Roxane Briseño, Carlos G. Grajales-Reyes, Gary E. Wu, Xiaodi Durai, Vivek Albring, Jörn Bagadia, Prachi Murphy, Theresa L. Murphy, Kenneth M. RAB43 facilitates cross-presentation of cell-associated antigens by CD8α+ dendritic cells |
| author_facet |
Kretzer, Nicole M. Theisen, Derek J. Tussiwand, Roxane Briseño, Carlos G. Grajales-Reyes, Gary E. Wu, Xiaodi Durai, Vivek Albring, Jörn Bagadia, Prachi Murphy, Theresa L. Murphy, Kenneth M. |
| author_sort |
Kretzer, Nicole M. |
| title |
RAB43 facilitates cross-presentation of cell-associated antigens by CD8α+ dendritic cells |
| title_short |
RAB43 facilitates cross-presentation of cell-associated antigens by CD8α+ dendritic cells |
| title_full |
RAB43 facilitates cross-presentation of cell-associated antigens by CD8α+ dendritic cells |
| title_fullStr |
RAB43 facilitates cross-presentation of cell-associated antigens by CD8α+ dendritic cells |
| title_full_unstemmed |
RAB43 facilitates cross-presentation of cell-associated antigens by CD8α+ dendritic cells |
| title_sort |
rab43 facilitates cross-presentation of cell-associated antigens by cd8α+ dendritic cells |
| description |
RAB43 is a vesicular transport protein unique to CD8α+ DCs that is localized to the Golgi. Kretzer et al. show that RAB43 is necessary for optimal cross-presentation of cell-associated antigens by CD8α+ DCs in vitro and in vivo but that it is dispensable for cross-presentation by in vitro monocyte-derived DCs. |
| publisher |
The Rockefeller University Press |
| publishDate |
2016 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154939/ |
| _version_ |
1613778941536894976 |