The ubiquitin hybrid gene UBA52 regulates ubiquitination of ribosome and sustains embryonic development

The ubiquitin hybrid gene UBA52 regulates ubiquitination of ribosome and sustains embryonic development

Ubiquitination is a crucial post-translational modification; however, the functions of ubiquitin-coding genes remain unclear. UBA52 encodes a fusion protein comprising ubiquitin at the N-terminus and ribosomal protein L40 (RPL40) at the C-terminus. Here we showed that Uba52-deficient mice die during...

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Bibliographic Details
Main Authors: Kobayashi, Masanori, Oshima, Shigeru, Maeyashiki, Chiaki, Nibe, Yoichi, Otsubo, Kana, Matsuzawa, Yu, Nemoto, Yasuhiro, Nagaishi, Takashi, Okamoto, Ryuichi, Tsuchiya, Kiichiro, Nakamura, Tetsuya, Watanabe, Mamoru
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103194/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103194/

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