RIG-I activation induces the release of extracellular vesicles with antitumor activity

RIG-I activation induces the release of extracellular vesicles with antitumor activity

Activation of the innate immune receptor retinoic acid-inducible gene I (RIG-I) by its specific ligand 5′-triphosphate-RNA (3pRNA) triggers antitumor immunity predominantly via NK cell activation and direct apoptosis induction in tumor cells. However, how NK cells are mobilized to attack the tumor c...

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Bibliographic Details
Main Authors: Daßler-Plenker, Juliane, Reiners, Katrin S., van den Boorn, Jasper G., Hansen, Hinrich P., Putschli, Bastian, Barnert, Sabine, Schuberth-Wagner, Christine, Schubert, Rolf, Tüting, Thomas, Hallek, Michael, Schlee, Martin, Hartmann, Gunther, Pogge von Strandmann, Elke, Coch, Christoph
Format: Online
Language:English
Published: Taylor & Francis 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087302/

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