DNA damage response and evasion from immunosurveillance in CLL: new options for NK cell-based immunotherapies

Chronic lymphocytic leukemia (CLL) is the most prominent B cell malignancy among adults in the Western world and characterized by a clonal expansion of B cells. The patients suffer from severe immune defects resulting in increased susceptibility to infections and failure to generate an antitumor imm...

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Bibliographic Details
Main Authors: Shatnyeva, Olga M., Hansen, Hinrich P., Reiners, Katrin S., Sauer, Maike, Vyas, Maulik, von Strandmann, Elke Pogge
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316781/