Plasma Tryptophan and the Kynurenine–Tryptophan Ratio Are Associated with the Acquisition of Statural Growth Deficits and Oral Vaccine Underperformance in Populations with Environmental Enteropathy

Plasma Tryptophan and the Kynurenine–Tryptophan Ratio Are Associated with the Acquisition of Statural Growth Deficits and Oral Vaccine Underperformance in Populations with Environmental Enteropathy

Early childhood enteric infections have adverse impacts on child growth and can inhibit normal mucosal responses to oral vaccines, two critical components of environmental enteropathy. To evaluate the role of indoleamine 2,3-dioxygenase 1 (IDO1) activity and its relationship with these outcomes, we...

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Bibliographic Details
Main Authors: Kosek, Margaret N., Mduma, Estomih, Kosek, Peter S., Lee, Gwenyth O., Svensen, Erling, Pan, William K. Y., Olortegui, Maribel Paredes, Bream, Jay H., Patil, Crystal, Asayag, Cesar Ramal, Sanchez, Graciela Meza, Caulfield, Laura E., Gratz, Jean, Yori, Pablo Peñataro
Format: Online
Language:English
Published: The American Society of Tropical Medicine and Hygiene 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062803/

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