13C-tryptophan breath test detects increased catabolic turnover of tryptophan along the kynurenine pathway in patients with major depressive disorder

13C-tryptophan breath test detects increased catabolic turnover of tryptophan along the kynurenine pathway in patients with major depressive disorder

Altered tryptophan–kynurenine (KYN) metabolism has been implicated in major depressive disorder (MDD). The l-[1-13C]tryptophan breath test (13C-TBT) is a noninvasive, stable-isotope tracer method in which exhaled 13CO2 is attributable to tryptophan catabolism via the KYN pathway. We included 18 pati...

Full description

Bibliographic Details
Main Authors: Teraishi, Toshiya, Hori, Hiroaki, Sasayama, Daimei, Matsuo, Junko, Ogawa, Shintaro, Ota, Miho, Hattori, Kotaro, Kajiwara, Masahiro, Higuchi, Teruhiko, Kunugi, Hiroshi
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630584/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630584/

Similar Items