Plasma Circulating Cell-free DNA Integrity as a Promising Biomarker for Diagnosis and Surveillance in Patients with Hepatocellular Carcinoma

The clinical significance of circulating cell-free DNA (cfDNA) integrity as diagnostic and surveillance biomarker in hepatocellular carcinoma (HCC) was investigated and compared to that of alpha fetoprotein (AFP). Liver cancer patients had lower cfDNA integrity than those with benign diseases (P = 0...

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Bibliographic Details
Main Authors: Huang, Ao, Zhang, Xin, Zhou, Shao-Lai, Cao, Ya, Huang, Xiao-Wu, Fan, Jia, Yang, Xin-Rong, Zhou, Jian
Format: Online
Language:English
Published: Ivyspring International Publisher 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039362/