Detecting Circulating Tumor DNA in Hepatocellular Carcinoma Patients Using Droplet Digital PCR Is Feasible and Reflects Intratumoral Heterogeneity

Detecting Circulating Tumor DNA in Hepatocellular Carcinoma Patients Using Droplet Digital PCR Is Feasible and Reflects Intratumoral Heterogeneity

Purpose: Circulating tumor DNA (ctDNA) is increasingly recognized as liquid biopsy to profile tumor genome. Droplet digital PCR (ddPCR) is a highly sensitive and easily operable platform for mutant detection. Here, we tried to detect ctDNA in hepatocellular carcinoma (HCC) patients using ddPCR.

Bibliographic Details
Main Authors: Huang, Ao, Zhang, Xin, Zhou, Shao-Lai, Cao, Ya, Huang, Xiao-Wu, Fan, Jia, Yang, Xin-Rong, Zhou, Jian
Format: Online
Language:English
Published: Ivyspring International Publisher 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039376/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039376/

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