PPM1D controls nucleolar formation by up-regulating phosphorylation of nucleophosmin

An increase of nucleolar number and size has made nucleoli essential markers for cytology and tumour development. However, the underlying basis for their structural integrity and abundance remains unclear. Protein phosphatase PPM1D was found to be up-regulated in different carcinomas including breas...

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Bibliographic Details
Main Authors: Kozakai, Yuuki, Kamada, Rui, Furuta, Junya, Kiyota, Yuhei, Chuman, Yoshiro, Sakaguchi, Kazuyasu
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020408/