The nucleolar protein nucleophosmin is essential for autophagy induced by inhibiting Pol I transcription

The nucleolar protein nucleophosmin is essential for autophagy induced by inhibiting Pol I transcription

Various cellular stresses activate autophagy, which is involved in lysosomal degradation of cytoplasmic materials for maintaining nutrient homeostasis and eliminating harmful components. Here, we show that RNA polymerase I (Pol I) transcription inhibition induces nucleolar disruption and autophagy....

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Bibliographic Details
Main Authors: Katagiri, Naohiro, Kuroda, Takao, Kishimoto, Hiroyuki, Hayashi, Yuki, Kumazawa, Takuya, Kimura, Keiji
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354046/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354046/

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