The Deficiency of Indoleamine 2,3-Dioxygenase Aggravates the CCl4-Induced Liver Fibrosis in Mice

The Deficiency of Indoleamine 2,3-Dioxygenase Aggravates the CCl4-Induced Liver Fibrosis in Mice

In the present study, we examined the role of indoleamine 2,3-dioxygenase (IDO) in the development of CCl4-induced hepatic fibrosis. The liver fibrosis induced by repetitive administration with CCl4 was aggravated in IDO-KO mice compared to WT mice. In IDO-KO mice treated with CCl4, the number of se...

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Bibliographic Details
Main Authors: Ogiso, Hideyuki, Ito, Hiroyasu, Ando, Tatsuya, Arioka, Yuko, Kanbe, Ayumu, Ando, Kazuki, Ishikawa, Tetsuya, Saito, Kuniaki, Hara, Akira, Moriwaki, Hisataka, Shimizu, Masahito, Seishima, Mitsuru
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012673/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012673/

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