The Role of Indoleamine 2,3-Dioxygenase in Diethylnitrosamine-Induced Liver Carcinogenesis

The Role of Indoleamine 2,3-Dioxygenase in Diethylnitrosamine-Induced Liver Carcinogenesis

Indoleamine 2,3-dioxygenase (IDO), a tryptophan-catabolizing intracellular enzyme of the L-kynurenine pathway, causes preneoplastic cells and tumor cells to escape the immune system by inducing immune tolerance; this mechanism might be associated with the development and progression of human maligna...

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Bibliographic Details
Main Authors: Shibata, Yuhei, Hara, Takeshi, Nagano, Junji, Nakamura, Nobuhiko, Ohno, Tomohiko, Ninomiya, Soranobu, Ito, Hiroyasu, Tanaka, Takuji, Saito, Kuniaki, Seishima, Mitsuru, Shimizu, Masahito, Moriwaki, Hisataka, Tsurumi, Hisashi
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699706/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699706/

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