The aryl hydrocarbon receptor controls cyclin O to promote epithelial multiciliogenesis
Epithelia function as barriers against environmental insults and express the transcription factor aryl hydrocarbon receptor (AhR). However, AhR function in these tissues is unknown. Here we show that AhR regulates multiciliogenesis in both murine airway epithelia and in Xenopus laevis epidermis. In...
Main Authors: | Villa, Matteo, Crotta, Stefania, Dingwell, Kevin S., Hirst, Elizabeth M. A., Gialitakis, Manolis, Ahlfors, Helena, Smith, James C., Stockinger, Brigitta, Wack, Andreas |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999520/ |
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