The aryl hydrocarbon receptor controls cyclin O to promote epithelial multiciliogenesis

The aryl hydrocarbon receptor controls cyclin O to promote epithelial multiciliogenesis

Epithelia function as barriers against environmental insults and express the transcription factor aryl hydrocarbon receptor (AhR). However, AhR function in these tissues is unknown. Here we show that AhR regulates multiciliogenesis in both murine airway epithelia and in Xenopus laevis epidermis. In...

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Bibliographic Details
Main Authors: Villa, Matteo, Crotta, Stefania, Dingwell, Kevin S., Hirst, Elizabeth M. A., Gialitakis, Manolis, Ahlfors, Helena, Smith, James C., Stockinger, Brigitta, Wack, Andreas
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999520/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999520/

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