Binding of polychlorinated biphenyls to the aryl hydrocarbon receptor.

A new thermodynamic model for calculating the dissociation constants of complexes formed between the aryl hydrocarbon receptor (AhR) and polychlorinated biphenyls (PCBs) is reported. The free energies of binding of PCBs to AhR are controlled by their lipophilicities, electron affinities, and entropi...

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Bibliographic Details
Main Authors: Kafafi, S A, Afeefy, H Y, Ali, A H, Said, H K, Kafafi, A G
Format: Online
Language:English
Published: 1993
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519849/