Total Synthesis of Putative 11-epi-Lyngbouilloside Aglycon
We report here the total synthesis of 11-epi-lyngbouilloside aglycon. Our strategy features a Boeckman-type esterification followed by a RCM to form the 14-membered ring macrolactone and a late-stage side chain introduction via a Wittig olefination. Overall, the final product was obtained in 20 step...
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Bibliographic Details
Main Authors: |
Kolleth, Amandine,
Gebauer, Julian,
ElMarrouni, Abdelatif,
Lebeuf, Raphael,
Prévost, Céline,
Brohan, Eric,
Arseniyadis, Stellios,
Cossy, Janine |
Format: | Online
|
Language: | English |
Published: |
Frontiers Media S.A.
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977289/
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