Total Synthesis of Putative 11-epi-Lyngbouilloside Aglycon

Total Synthesis of Putative 11-epi-Lyngbouilloside Aglycon

We report here the total synthesis of 11-epi-lyngbouilloside aglycon. Our strategy features a Boeckman-type esterification followed by a RCM to form the 14-membered ring macrolactone and a late-stage side chain introduction via a Wittig olefination. Overall, the final product was obtained in 20 step...

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Bibliographic Details
Main Authors: Kolleth, Amandine, Gebauer, Julian, ElMarrouni, Abdelatif, Lebeuf, Raphael, Prévost, Céline, Brohan, Eric, Arseniyadis, Stellios, Cossy, Janine
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977289/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977289/

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