Whole-animal genome-wide RNAi screen identifies networks regulating male germline stem cells in Drosophila
Stem cells are regulated both intrinsically and externally, including by signals from the local environment and distant organs. To identify genes and pathways that regulate stem-cell fates in the whole organism, we perform a genome-wide transgenic RNAi screen through ubiquitous gene knockdowns, focu...
Main Authors: | Liu, Ying, Ge, Qinglan, Chan, Brian, Liu, Hanhan, Singh, Shree Ram, Manley, Jacob, Lee, Jae, Weideman, Ann Marie, Hou, Gerald, Hou, Steven X. |
---|---|
Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976209/ |
Similar Items
-
FlyRNAi: the Drosophila RNAi screening center database
by: Flockhart, Ian, et al.
Published: (2006) -
The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis
by: Singh, Shree Ram, et al.
Published: (2016) -
The Nuclear Matrix Protein Megator Regulates Stem Cell Asymmetric Division through the Mitotic Checkpoint Complex in Drosophila Testes
by: Liu, Ying, et al.
Published: (2015) -
Repression of Germline RNAi Pathways in Somatic Cells by Retinoblastoma Pathway Chromatin Complexes
by: Wu, Xiaoyun, et al.
Published: (2012) -
FlyRNAi.org—the database of the Drosophila RNAi screening center: 2012 update
by: Flockhart, Ian T., et al.
Published: (2012)