Whole-animal genome-wide RNAi screen identifies networks regulating male germline stem cells in Drosophila

Stem cells are regulated both intrinsically and externally, including by signals from the local environment and distant organs. To identify genes and pathways that regulate stem-cell fates in the whole organism, we perform a genome-wide transgenic RNAi screen through ubiquitous gene knockdowns, focu...

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Bibliographic Details
Main Authors: Liu, Ying, Ge, Qinglan, Chan, Brian, Liu, Hanhan, Singh, Shree Ram, Manley, Jacob, Lee, Jae, Weideman, Ann Marie, Hou, Gerald, Hou, Steven X.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976209/