RNAi Screening of Drosophila (Sophophora) melanogaster S2 Cells for Ricin Sensitivity and Resistance
The ribosome-inhibiting toxin ricin binds exposed β1→4 linked galactosyls on multiple glycolipids and glycoproteins on the cell surface of most eukaryotic cells. After endocytosis, internal cell trafficking is promiscuous, with only a small proportion of ricin proceeding down a productive (cytotoxic...
| Main Authors: | , , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
SAGE Publications
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764841/ |