Control of the Inflammatory Macrophage Transcriptional Signature by miR-155
Inflammatory M1 spectrum macrophages protect from infection but can cause inflammatory disease and tissue damage, whereas alternatively activated/M2 spectrum macrophages reduce inflammation and promote tissue repair. Modulation of macrophage phenotype may be therapeutically beneficial and requires f...
Main Authors: | Jablonski, Kyle A., Gaudet, Andrew D., Amici, Stephanie A., Popovich, Phillip G., Guerau-de-Arellano, Mireia |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957803/ |
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