Differential activation and functional specialization of miR-146 and miR-155 in innate immune sensing

Many microRNAs (miRNAs) are co-regulated during the same physiological process but the underlying cellular logic is often little understood. The conserved, immunomodulatory miRNAs miR-146 and miR-155, for instance, are co-induced in many cell types in response to microbial lipopolysaccharide (LPS) t...

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Bibliographic Details
Main Authors: Schulte, Leon N., Westermann, Alexander J., Vogel, Jörg
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592429/