Fibroblast-Derived MMP-14 Regulates Collagen Homeostasis in Adult Skin

Proteolytic activities in the extracellular matrix by the matrix metalloproteinase (MMP)-14 have been implicated in the remodeling of collagenous proteins during development. To analyze the function of fibroblast-derived MMP-14 in adult skin homeostasis, we generated mice with inducible deletion of...

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Bibliographic Details
Main Authors: Zigrino, Paola, Brinckmann, Jürgen, Niehoff, Anja, Lu, Yinhui, Giebeler, Nives, Eckes, Beate, Kadler, Karl E., Mauch, Cornelia
Format: Online
Language:English
Published: Elsevier 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946792/