Chick tendon fibroblast transcriptome and shape depend on whether the cell has made its own collagen matrix

Collagen- and fibrin-based gels are extensively used to study cell behaviour. However, 2D–3D and collagen-fibrin comparisons of gene expression, cell shape and mechanotransduction, with an in vivo reference, have not been reported. Here we compared chick tendon fibroblasts (CTFs) at three stages of...

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Bibliographic Details
Main Authors: Yeung, Ching-Yan Chloé, Zeef, Leo A. H., Lallyett, Chloe, Lu, Yinhui, Canty-Laird, Elizabeth G., Kadler, Karl E.
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559659/