Stepwise proteolytic activation of type I procollagen to collagen within the secretory pathway of tendon fibroblasts in situ
Proteolytic cleavage of procollagen I to collagen I is essential for the formation of collagen fibrils in the extracellular matrix of vertebrate tissues. Procollagen is cleaved by the procollagen N- and C-proteinases, which remove the respective N- and C-propeptides from procollagen. Procollagen pro...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Portland Press Ltd.
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430002/ |