Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality

Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality

Fibroblastic reticular cells (FRCs) form the cellular scaffold of lymph nodes (LNs) and establish distinct microenvironmental niches to provide key molecules that drive innate and adaptive immune responses and control immune regulatory processes. Here, we have used a graph theory-based systems biolo...

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Bibliographic Details
Main Authors: Novkovic, Mario, Onder, Lucas, Cupovic, Jovana, Abe, Jun, Bomze, David, Cremasco, Viviana, Scandella, Elke, Stein, Jens V., Bocharov, Gennady, Turley, Shannon J., Ludewig, Burkhard
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945005/

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