Dendritic Cells Control Fibroblastic Reticular Network Tension and Lymph Node Expansion

Dendritic Cells Control Fibroblastic Reticular Network Tension and Lymph Node Expansion

Following immunogenic challenge, infiltrating and dividing lymphocytes significantly increase lymph node (LN) cellularity leading to organ expansion1,2. Here we report that the physical elasticity of LNs is maintained in part by podoplanin (PDPN) signalling in stromal fibroblastic reticular cells (F...

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Bibliographic Details
Main Authors: Acton, Sophie E., Farrugia, Aaron J., Astarita, Jillian L., Mourão-Sá, Diego, Jenkins, Robert P., Nye, Emma, Hooper, Steven, van Blijswijk, Janneke, Rogers, Neil C., Snelgrove, Kathryn J., Rosewell, Ian, Moita, Luis F., Stamp, Gordon, Turley, Shannon J., Sahai, Erik, Sousa, Caetano Reis e
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235005/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235005/

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