Lymph node topology dictates T cell migration behavior
Adaptive immunity is initiated by T cell recognition of foreign peptides presented on dendritic cells (DCs) by major histocompatibility molecules. These interactions take place in secondary lymphoid tissues, such as lymph nodes (LNs) and spleen, and hence the anatomical structure of these tissues pl...
Main Authors: | , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2007
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118562/ |