Secretion of protein disulphide isomerase AGR2 confers tumorigenic properties

The extracellular matrix (ECM) plays an instrumental role in determining the spatial orientation of epithelial polarity and the formation of lumens in glandular tissues during morphogenesis. Here, we show that the Endoplasmic Reticulum (ER)-resident protein anterior gradient-2 (AGR2), a soluble prot...

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Bibliographic Details
Main Authors: Fessart, Delphine, Domblides, Charlotte, Avril, Tony, Eriksson, Leif A, Begueret, Hugues, Pineau, Raphael, Malrieux, Camille, Dugot-Senant, Nathalie, Lucchesi, Carlo, Chevet, Eric, Delom, Frederic
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940162/