Reticulon1-C modulates protein disulphide isomerase function

Endoplasmic reticulum (ER) is the primary site for the synthesis and folding of secreted and membrane-bound proteins. Accumulation of unfolded and misfolded proteins in ER underlies a wide range of human neurodegenerative disorders. Hence, molecules regulating the ER stress response represent potent...

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Bibliographic Details
Main Authors: Bernardoni, P, Fazi, B, Costanzi, A, Nardacci, R, Montagna, C, Filomeni, G, Ciriolo, M R, Piacentini, M, Di Sano, F
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641336/