Mechanisms of Neuroprotection by Protein Disulphide Isomerase in Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterised by the progressive loss of motor neurons, leading to paralysis and death within several years of onset. Although protein misfolding is a key feature of ALS, the upstream triggers of disease remain elusive. R...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096316/ |