In-situ coupling between kinase activities and protein dynamics within single focal adhesions
The dynamic activation of oncogenic kinases and regulation of focal adhesions (FAs) are crucial molecular events modulating cell adhesion in cancer metastasis. However, it remains unclear how these events are temporally coordinated at single FA sites. Therefore, we targeted fluorescence resonance en...
Main Authors: | Wu, Yiqian, Zhang, Kaiwen, Seong, Jihye, Fan, Jason, Chien, Shu, Wang, Yingxiao, Lu, Shaoying |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935953/ |
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