In-situ coupling between kinase activities and protein dynamics within single focal adhesions

The dynamic activation of oncogenic kinases and regulation of focal adhesions (FAs) are crucial molecular events modulating cell adhesion in cancer metastasis. However, it remains unclear how these events are temporally coordinated at single FA sites. Therefore, we targeted fluorescence resonance en...

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Bibliographic Details
Main Authors: Wu, Yiqian, Zhang, Kaiwen, Seong, Jihye, Fan, Jason, Chien, Shu, Wang, Yingxiao, Lu, Shaoying
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935953/