Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition

Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition

The inflammasome NLRP3 is activated by pathogen associated molecular patterns (PAMPs) during infection, including RNA and proteins from influenza A virus (IAV). However, chronic activation by danger associated molecular patterns (DAMPs) can be deleterious to the host. We show that blocking NLRP3 act...

Full description

Bibliographic Details
Main Authors: Tate, Michelle D., Ong, James D. H., Dowling, Jennifer K., McAuley, Julie L., Robertson, Avril B., Latz, Eicke, Drummond, Grant R., Cooper, Matthew A., Hertzog, Paul J., Mansell, Ashley
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901306/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901306/

Similar Items