The role of the NLRP3 inflammasome in gout
Gout is an inflammatory arthritis characterized by abrupt self-limiting attacks of inflammation caused by precipitation of monosodium urate crystals (MSU) in the joint. Recent studies suggest that orchestration of the MSU-induced inflammatory response is dependent on the proinflammatory cytokine IL-...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Dove Medical Press
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218743/ |