EM23, a natural sesquiterpene lactone, targets thioredoxin reductase to activate JNK and cell death pathways in human cervical cancer cells
Sesquiterpene lactones (SLs) are the active constituents of a variety of medicinal plants and found to have potential anticancer activities. However, the intracellular molecular targets of SLs and the underlying molecular mechanisms have not been well elucidated. In this study, we observed that EM23...
Main Authors: | Shao, Fang-Yuan, Wang, Sheng, Li, Hong-Yu, Chen, Wen-Bo, Wang, Guo-Cai, Ma, Dong-Lei, Wong, Nai Sum, Xiao, Hao, Liu, Qiu-Ying, Zhou, Guang-Xiong, Li, Yao-Lan, Li, Man-Mei, Wang, Yi-Fei, Liu, Zhong |
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Format: | Online |
Language: | English |
Published: |
Impact Journals LLC
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872749/ |
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