EM23, a natural sesquiterpene lactone, targets thioredoxin reductase to activate JNK and cell death pathways in human cervical cancer cells

EM23, a natural sesquiterpene lactone, targets thioredoxin reductase to activate JNK and cell death pathways in human cervical cancer cells

Sesquiterpene lactones (SLs) are the active constituents of a variety of medicinal plants and found to have potential anticancer activities. However, the intracellular molecular targets of SLs and the underlying molecular mechanisms have not been well elucidated. In this study, we observed that EM23...

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Bibliographic Details
Main Authors: Shao, Fang-Yuan, Wang, Sheng, Li, Hong-Yu, Chen, Wen-Bo, Wang, Guo-Cai, Ma, Dong-Lei, Wong, Nai Sum, Xiao, Hao, Liu, Qiu-Ying, Zhou, Guang-Xiong, Li, Yao-Lan, Li, Man-Mei, Wang, Yi-Fei, Liu, Zhong
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872749/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872749/

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