Cancer mutation signatures, DNA damage mechanisms, and potential clinical implications

by Harris, Reuben S
Published 2013

Molecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancer

by Harris, Reuben S
Published 2015

Evolutionary Paradigms from Ancient and Ongoing Conflicts between the Lentiviral Vif Protein and Mammalian APOBEC3 Enzymes

by Harris, Reuben S., Anderson, Brett D.
Published 2016

Transcriptional regulation of APOBEC3 antiviral immunity through the CBF-β/RUNX axis

by Anderson, Brett D., Harris, Reuben S.
Published 2015

Endogenous Origins of HIV-1 G-to-A Hypermutation and Restriction in the Nonpermissive T Cell Line CEM2n

by Refsland, Eric W., Hultquist, Judd F., Harris, Reuben S.
Published 2012

The Restriction of Zoonotic PERV Transmission by Human APOBEC3G

by Jónsson, Stefán R., LaRue, Rebecca S., Stenglein, Mark D., Fahrenkrug, Scott C., Andrésdóttir, Valgerdur, Harris, Reuben S.
Published 2007

Evolutionarily conserved and non-conserved retrovirus restriction activities of artiodactyl APOBEC3F proteins

by Jónsson, Stefán R., Haché, Guylaine, Stenglein, Mark D., Fahrenkrug, Scott C., Andrésdóttir, Valgerdur, Harris, Reuben S.
Published 2006

Interaction of APOBEC3A with DNA Assessed by Atomic Force Microscopy

by Shlyakhtenko, Luda S., Lushnikov, Alexander J., Li, Ming, Harris, Reuben S., Lyubchenko, Yuri L.
Published 2014

APOBEC3G Interacts with ssDNA by Two Modes: AFM Studies

by Shlyakhtenko, Luda S., Dutta, Samrat, Banga, Jaspreet, Li, Ming, Harris, Reuben S., Lyubchenko, Yuri L.
Published 2015

DNA-Dependent Protein Kinase Inhibits AID-Induced Antibody Gene Conversion

by Cook, Adam J. L, Raftery, Joanna M, Lau, K. K. Edwin, Jessup, Andrew, Harris, Reuben S, Takeda, Shunichi, Jolly, Christopher J
Published 2007

A Comparison of Two Single-Stranded DNA Binding Models by Mutational Analysis of APOBEC3G

by Shindo, Keisuke, Li, Ming, Gross, Phillip J., Brown, William L., Harjes, Elena, Lu, Yongjian, Matsuo, Hiroshi, Harris, Reuben S.
Published 2012

Degradation of the cancer genomic DNA deaminase APOBEC3B by SIV Vif

by Land, Allison M., Wang, Jiayi, Law, Emily K., Aberle, Ryan, Kirmaier, Andrea, Krupp, Annabel, Johnson, Welkin E., Harris, Reuben S.
Published 2015

APOBEC3 inhibits DEAD-END function to regulate microRNA activity

by Ali, Sara, Karki, Namrata, Bhattacharya, Chitralekha, Zhu, Rui, MacDuff, Donna A, Stenglein, Mark D, Schumacher, April J, Demorest, Zachary L, Harris, Reuben S, Matin, Angabin, Aggarwal, Sita
Published 2013

Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B

by Akre, Monica K., Starrett, Gabriel J., Quist, Jelmar S., Temiz, Nuri A., Carpenter, Michael A., Tutt, Andrew N. J., Grigoriadis, Anita, Harris, Reuben S.
Published 2016

Structure of the Vif-binding domain of the antiviral enzyme APOBEC3G

by Kouno, Takahide, Luengas, Elizabeth M., Shigematsu, Megumi, Shandilya, Shivender M.D., Zhang, JingYing, Chen, Luan, Hara, Mayuko, Schiffer, Celia A., Harris, Reuben S., Matsuo, Hiroshi
Published 2015

A Naturally Occurring Domestic Cat APOBEC3 Variant Confers Resistance to Feline Immunodeficiency Virus Infection

by Yoshikawa, Rokusuke, Izumi, Taisuke, Yamada, Eri, Nakano, Yusuke, Misawa, Naoko, Ren, Fengrong, Carpenter, Michael A., Ikeda, Terumasa, Münk, Carsten, Harris, Reuben S., Miyazawa, Takayuki, Koyanagi, Yoshio, Sato, Kei
Published 2015

Natural Polymorphisms in Human APOBEC3H and HIV-1 Vif Combine in Primary T Lymphocytes to Affect Viral G-to-A Mutation Levels and Infectivity

by Refsland, Eric W., Hultquist, Judd F., Luengas, Elizabeth M., Ikeda, Terumasa, Shaban, Nadine M., Law, Emily K., Brown, William L., Reilly, Cavan, Emerman, Michael, Harris, Reuben S.
Published 2014

Small molecules that inhibit Vif-induced degradation of APOBEC3G

by Matsui, Masashi, Shindo, Keisuke, Izumi, Taisuke, Io, Katsuhiro, Shinohara, Masanobu, Komano, Jun, Kobayashi, Masayuki, Kadowaki, Norimitsu, Harris, Reuben S, Takaori-Kondo, Akifumi
Published 2014

Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G

by Stanley, David J., Bartholomeeusen, Koen, Crosby, David C., Kim, Dong Young, Kwon, Eunju, Yen, Linda, Cartozo, Nathalie Caretta, Li, Ming, Jäger, Stefanie, Mason-Herr, Jeremy, Hayashi, Fumiaki, Yokoyama, Shigeyuki, Krogan, Nevan J., Harris, Reuben S., Peterlin, Boris Matija, Gross, John D.
Published 2012

DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer

by Kanu, Nnennaya, Cerone, Maria Antonietta, Goh, Gerald, Zalmas, Lykourgos-Panagiotis, Bartkova, Jirina, Dietzen, Michelle, McGranahan, Nicholas, Rogers, Rebecca, Law, Emily K., Gromova, Irina, Kschischo, Maik, Walton, Michael I., Rossanese, Olivia W., Bartek, Jiri, Harris, Reuben S., Venkatesan, Subramanian, Swanton, Charles
Published 2016