Post-translational control of RIPK3 and MLKL mediated necroptotic cell death

Several programmed lytic and necrotic-like cell death mechanisms have now been uncovered, including the recently described receptor interacting protein kinase-3 (RIPK3)-mixed lineage kinase domain-like (MLKL)-dependent necroptosis pathway. Genetic experiments have shown that programmed necrosis, inc...

Full description

Bibliographic Details
Main Authors: Murphy, James M., Vince, James E.
Format: Online
Language:English
Published: F1000Research 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851234/